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The Bensinger laboratory is focused on defining how lipid metabolism directs the fate and function of cells. In particular, we are trying to elucidate the molecular circuitry regulating lipid homeostasis in rapidly dividing normal and neoplastic cells.  Using a combination of molecular biology and analytical chemistry approaches, we are trying to define the molecular signals and enzymatic pathways that dictate how a cell regulates lipid homeostasis. One important area of study is focused on determining how lipid metabolism influences the development of the immune system and host immunity to pathogens. In parallel, we are actively investigating how growth signals direct the lipid metabolic programming of normal cells, and determine if these pathways become dysregulated during carcinogenesis.