The Research Team
The Bensinger Lab and the UCLA Lipidomics Lab are composed of outstanding scientists from around the world. These laboratories have undergraduate and graduate researchers, postdoctoral fellows, and staff scientists driving scientific discoveries. Learn more about the people in the labs, past and present, and explore their research below.
Steven Bensinger
Dr. Bensinger received his veterinary medical degree and his doctoral degree in Immunology from the University of Pennsylvania. He completed a thesis on regulatory T-cell development and function in the laboratory of Dr. Laurence Turka, followed by a postdoctoral fellowship in the laboratory of Dr. Peter Tontonoz at UCLA, where he examined the impact of lipid metabolism on T-cell growth and survival. Dr. Bensinger has received several professional honors, including the Sontag Foundation Distinguished Scientist Award and the 2016 UCLA Life Sciences Excellence Award for Outstanding Research. In 2018, Dr. Bensinger received the Sherie and Donald Morrison Chair in Immunology. Dr. Bensinger’s interests outside the lab includes hiking, mountain biking, watching his kids play soccer, and baking.
Principle Investigator
Bensinger Laboratory
Professor, MIMG
Professor, MMP
Director, UCLA Lipdiomics Lab
Kevin Williams
Kevin Williams did his PhD work in the lab of Dr. Stephen Smale studying
transcriptional regulation in the immune response. During his post-doctoral
fellowship in Steven Bensinger lab, Kevin studied SREBP regulation of the lipid
metabolic program in cancer cell models. This work required a number of lipid
mass spectrometry experiments and led to his involvement in numerous projects in
the lab involving isotope labeling and high throughput sample preparation for mass
spectrometry. In 2017, Kevin leveraged this expertise to launch the UCLA
Lipidomics Lab with professors Steven Bensinger and James Wohlschlegel. This
core facility now analyzes thousands of samples per year and supports lipidomic
research all around the world.
Scientific Director
UCLA Lipdiomics Lab
Scientist, Biological Chemistry at UCLA
Richard Watson
Dr. Richard Watson is a pulmonary and critical care physician with a joint appointment at UCLA and the Greater Los Angeles Veterans Affairs Healthcare System. He is currently completing his postdoctoral studies in the Bensinger Lab. Originally from metro Detroit, Richard completed his undergraduate studies at the University of Michigan before going to Northwestern University for a combined MD/PhD program. Following medical school, he completed an internal medicine residency at Cedars-Sinai, followed by a pulmonary/critical care fellowship at UCLA. Richard joined the Bensinger Lab in March 2020, partway through his fellowship training. His project focuses on understanding the role of lipid immunometabolism in pulmonary disease. Initial studies are aimed at understanding specifically the role of fatty acid metabolism and stearoyl-CoA desaturase (SCD) function in pulmonary fibrosis, mirroring his clinical focus. Outside of the lab, Richard enjoys spending time with his wife (a fellow scientist and current professor at UC Irvine), dog, two cats, and friends. Between science and medicine, Richard tries to find time to explore LA, go to concerts/music festivals, and take advantage of the continuous perfect weather by running, golfing, surfing, and mountain biking.
Post Doctoral Fellow
Tianheng Hou
Tianheng received his M.S. from SJTU (Shanghai Jiao Tong University) majoring in pharmacy and his Ph.D. from CUHK (The Chinese University of Hong Kong) majoring in immunology. His Ph.D. research focused on elucidating the cytokine and chemokine network and intracellular signal mechanism in allergic diseases. He recently joined the Bensinger lab as a postdoctoral scholar. In the Bensinger lab, He was interested in lipid metabolism and the interaction between lipids and genes. Outside the lab, Tianheng loves to watch movies, listen to top trending sounds, and walk around the city with friends.
Post Doctoral Fellow
Min-Sub Lee
Min Sub received his undergraduate degree in 2017 from UCLA in Microbiology and Immunology, with a specialty in Economics & Finances. He started as a graduate student in the Bensinger lab during the summer of 2019. His thesis project is focused on understanding the regulation and remodeling of lipid homeostasis in innate immune cells and how this alters their fate and function. Min-Sub is also study if lipid metabolic reprogramming can be exploited to protect tissues and cells from bacterial toxins that target plasma membrane lipids as a novel approach to decreasing the severe tissue damage observed in necrotizing soft tissue infections.
Graduate Student Researcher
Kelly Kennewick
Kelly is a senior graduate student and a Gilliam/HHMI scholar. She grew up in Seattle and later attended University of Washington where she received her BS in Biochemistry. She then moved down to Los Angeles and began working as a research associate in the Forman Lab at City of Hope. There, she developed and optimized CAR T cells for the treatment of bone metastatic prostate cancer. After four years at City of Hope, she began graduate school at UCLA. She now works in the lab of Dr. Steven Bensinger exploring questions regarding the crosstalk between lipid metabolism and T cell immunity. Her current projects include applying advanced mass spectrometry–based analytic approaches to explore the relationship between lipid composition and T cell function in healthy and disease states.
Graduate Student Researcher
Ian Ford
Ian graduated from Southern Methodist University in Dallas, Texas in 2016 and his research is focused on identifying the mechanism by which cholesterol regulates STING-dependent IFN signaling. He uses a number of tools to investigate regulation of STING by cholesterol, including but not limited to a photo-crosslinkable cholesterol-mimetic probe for chemoproteomic methods and confocal microscopy to assess activity-dependent translocation. These findings will allow us to begin to unravel the tangled web of links between sterol metabolism and immune activity, and potentially allow for the development of new therapies for IFN-linked autoimmune disorders and enhancement of current anti-tumor immunotherapy approaches.
Graduate Student Researcher
Palik Joulakian
Palik received her B.S. in Physiological Science from UCLA in 2021. Prior to that, she was a pharmacy student at LIU, Lebanon. She joined the Bensinger lab in 2022 as a staff research associate. Her project entails investigating the lipid metabolism of various genetic background models with the activation of macrophages with different stimuli of TLR agonists to see how the lipid composition changes. Outside of the lab, Palik enjoys hiking, swimming, traveling and sightseeing.
Staff Research Associate
Jonathan Quintana
Jon received his B.S in Biochemistry from UCLA in 2022. He joined the Bensinger Lab in the summer the same year assisting with ongoing projects related to lipid metabolism and immune response in addition to lab maintenance. Outside of lab Jon enjoys spending time with his two cats , playing video games and cooking.
Staff Research Associate
Gino Su
Gino received his B.S in statistics from UCLA. His works in the lipidomics core involve lipid mass spectrometry data analysis, modeling and data processing pipeline.
Staff Research Associate
Margarita Calderon
Margarita has been working with the members of the Bensinger lab for over 15 years. She provides amazing support to all of the studies in the lab and is integral part of our success.
Lab Assistant
Austin Sun
Austin is a fourth year undergraduate majoring in Molecular, Cellular, and Developmental Biology. His studies in the lab involve characterizing how deficiencies of cholesterol homeostatic genes in macrophages influence their inflammatory response. He enjoys playing basketball, golf and exploring restaurants around LA.
Undergraduate Researcher
Natalie Santillano
Natalie is a fourth year undergraduate majoring in Microbiology, Immunology, and Molecular Genetics. Her studies in the lab involve characterizing how cholesterol metabolic machinery of T cells influence their growth and function.
Lab Assistant
Naman Jain
Naman is an undergraduate Molecular, Cellular, & Developmental Biology major graduating in 2024. His studies in lab revolve around the effect of statins on T lymphocyte function. Some of his hobbies are playing the saxophone, watching k-dramas, and watching the NBA.
Undergraduate Researcher
Megan Husley
Megan is a 3rd year majoring in Microbiology, Immunology, and Molecular Genetics. Her work in Path 2 will study the link between perturbed cholesterol homeostasis and STING. Some of her hobbies include going to amusement parks, playing video games, and watching horror movies.
Undergraduate Researcher
Lab Alumni
Alessandro Sammarco
Postdoctoral Fellow
Alessandro received his Veterinary Medicine degree in 2014 and his Ph.D. degree in 2019 from the University of Padua, Italy. He completed a thesis on mammary gland cancer of dogs, cats, and women. Thanks to the support of the American-Italian Cancer Foundation, in 2020, he joined Dr Badr Lab at the Massachusetts General Hospital as a postdoctoral fellow, where he studied the efficacy of a brain-penetrant SCD inhibitor to treat glioblastoma and breast cancer brain metastasis. In 2021, Alessandro moved to Los Angeles in Dr Bensinger Lab as a postdoctoral fellow to study more in depth the role of lipid metabolism in cancer cells as well as in immune cells in brain tumors. Also, he is exploring the role of lipid metabolism during maturation and activation of dendritic cells and how perturbation of lipid metabolism determines their function. Beside science, Alessandro loves biking. When he is not in the lab, you can likely find him on his road bike in the stunning cycling climbs of the Santa Monica Mountains.
Autumn York
Graduate Student Researcher
Autumn's thesis work was focused on the molecular mechanisms by which lipid metabolism shaped inflammatory responses and anti-viral immunity. In 2015, Autumn York discovered that cholesterol and STING signaling are linked. Dr. York graduated from UCLA in 2015 and is a HHMI/ Hanna Grey Fellow in the laboratory of Dr. Richard Flavell at Yale University.
Joe Argus
Graduate Student Researcher
Joseph was a graduate student in the Molecular and Medical Pharmacology graduate program and completed his thesis in the Bensinger lab at UCLAJoseph's research focused on the development of new tools to assess fatty acid metabolism. Dr. Argus graduated in 2017 and was a postdoctoral fellow in the laboratory of Dr. Ed Dennis at UCSD. He is currently a senior scientist dealing with analytical R and D at Nitto Biopharma, Inc. since August of 2020.
Xun Allison Chi
Postdoctoral Fellow
Allison was a postdoctoral fellow in the Bensinger laboratory exploring how lipid metabolism influenced anti-microbial immunity. Allison received her B.S. from Zhejiang University, China, majoring in biotechnology. Her undergraduate research focused on how Shewanella Oneidensis develops natural resistance to Ampicillin. She completed her PhD at the University of Iowa in the laboratory of Dr. Brandon Davies. Her thesis focused on understanding the regulation of lipoprotein lipase (LPL) function by angiopoietin-like proteins (ANGPTLs). Allison is currently a Data Scientist at Health IQ.
Wei Yuan Wayne Hsieh
Postdoctoral Fellow
Wayne was a postdoctoral fellow in the Bensinger laboratory investigating how lipid metabolism influenced innate immune cell differentiation and function. Wayne received an Honours of Bachelor Science in Biological Sciences from University of Toronto. He undertook a doctoral thesis in the laboratory of Peter Ghazal at University of Edinburgh. His graduate studies were focused on elucidating the key role that interferons play in the regulation of cholesterol metabolism in anti-viral responses. Wayne’s postdoctoral studies continued the theme of immuno-metabolism where he investigated how lipid metabolic reprogramming and mitochondria function modulate macrophage polarization and anti-inflammatory function. Wayne is currently a Scientist at Emergent BioSolutions.
Quan Dylan Zhou
Graduate Student
Researcher
Dylan was a combined degree student in the Bensinger lab. She completed her medical training at Zhejiang University in China and was a graduate student in the Molecular and Medical Pharmacology graduate program at UCLA. Her thesis work focused on how cholesterol metabolism and the Interferon (IFN) response are intertwined. Her work showed that a small, but critical pool of cholesterol in the plasma membrane called the accessible cholesterol pool is rapidly depleted by interferon signaling. As a consequence of these changes in cholesterol metabolism, macrophages become resistant to bacterial toxins that target cholesterol in the membrane to kill host cells. Dylan is currently a principal investigator at Zhejiang University in China investigating crosstalk between lipid metabolism and macrophage immune responses since December of 2020.
Yoko Kidani
Post Doctoral Fellow
Yoko was a postdoctoral fellow in the Bensinger laboratory focused on understanding the impact of lipid metabolism on T cell growth, differentiation and effector function. Yoko received her medical training at the Graduate School of Medical Science, Kanazawa University, Kanazawa, Japan. She completed a residency in anesthesiology and intensive care medicine at Koseiren-Takaoka Hospital, Toyama, Japan. Yoko subsequently completed a thesis project examining the influence of anesthesia on endotoxin-induced shock in rats in the laboratory of Dr. Takumi Taniguchi, at Graduate School of Medical Science, Kanazawa University, Kanazawa, Japan. After completing her Yoko postdoctoral fellowship in the Bensinger laboratory she joined industry as a physician scientist. She is currently the Medical Head of Rare Blood Disorders at Sanofi.
Eliza Kroenberger
Staff Research Associate
Eliza graduated from Lewis & Clark College in 2017 with a degree in Biology. She served as a research assistant at the Oregon Health & Science University, working to integrate electrospray ionization with cryo-EM to advance super-resolution 3D-modeling of macromolecules. Following graduation, she researched the metabolic and physiological effects of pheromone exposure on D. melanogaster at the University of Hawai'i at Manoa. In the Bensinger lab, she assisted with ongoing projects related to lipid metabolism and immune response, in addition to performing lab maintenance. Currently, she is a Washington Conservation Corps Crew Member at the Washington State Departmemt of Ecology in Seattle since October 2020.